glaucomatous optic neuropathy management: the role of neuroprotective agents

نویسندگان

marianne l. shahsuvaryan

چکیده

glaucoma is a major cause of worldwide irreversible blindness. the central role of raised intraocular pressure (iop) is being questioned as many patients continue to demonstrate a clinically downhill course despite initial control of iop. the latest concept of recognizing glaucoma as a multifactorial, progressive, neurodegenerative disease of retinal ganglion cells (rgcss) associated with characteristic axon degeneration in the optic nerve emphasizes that several pressure-independent mechanisms are responsible for the development and progression of glaucomatous optic neuropathy. neuroprotection as a pharmacological strategy to mitigate retinal ganglion cell death has been a popular current approach. the aim of this review is to evaluate the neuroprotective potential of calcium channel blockers in glaucomatous optic neuropathy.

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عنوان ژورنال:
medical hypothesis, discovery and innovation ophthalmology journal

جلد ۲، شماره ۲، صفحات ۴۱-۰

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